WebA trial looking at using irinotecan beads for bowel cancer that had spread to the liver (PARAGON II) Cancer type: Bowel (colorectal) cancer Colon cancer Rectal cancer Secondary cancers Status: Results Phase: Phase 2 This trial looked at using irinotecan beads to treat bowel cancer that had spread to the liver, before having surgery to remove it. WebAug 29, 2024 · The PARAGON-HF trial randomized 4796 patients who were followed up for a median of 35 months, whereas the EMPEROR-Preserved trial randomized 5988 patients who were followed up for a median of 26 months. For the composite of cardiovascular death and total hospitalizations for heart failure, the incidence rates for the control groups were ...
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WebThe PARAGON-HF (Prospective Comparison of ARNI with ARB Global Outcomes in HF With Preserved Ejection Fraction) trial is designed to determine the efficacy and safety of the angiotensin receptor neprilysin inhibitor sacubitril/valsartan compared with valsartan in patients with chronic heart failure and preserved ejection fraction (HFpEF). WebNov 18, 2024 · The PARAGON-HF (ClinicalTrials.gov number, NCT01920711) investigated HF subjects class II to IV HF, ejection fraction of 45% or higher, elevated level of … エッセンシャルオイル 冬
Heart Failure and a Preserved Ejection Fraction: A Side-by-Side ...
WebJul 29, 2024 · PARAGON-HF follows the only positive Phase II trial in HFpEF, PARAMOUNT-HF, which demonstrated that sacubitril/valsartan reduced NT-proBNP (a biomarker of cardiac strain) to a greater extent than ... WebJul 29, 2024 · PARAGON-HF follows the only positive Phase II trial in HFpEF, PARAMOUNT-HF, which demonstrated that sacubitril/valsartan reduced NT-proBNP (a biomarker of cardiac strain) to a greater extent than valsartan at 12 weeks and was associated with improvement in NYHA class at 36 weeks. WebMay 20, 2013 · Methods: PARAGON is phase II Gynecologic Cancer InterGroup trial lead by the Australia New Zealand Gynaecological Oncology Group, Cancer Research UK and the Belgian Gynaecological Oncology Group. The study is designed to facilitate research in rare tumours. The protocol allows postmenopausal women with recurrent gynaecological … エッセンシャルオイル 使い方