Oxer1
WebOXER1 is a Chemoattractant Receptor for eosinophils and neutrophils. OXER1 has been reported to be expressed in liver, lung, kidney, peripheral blood leukocytes, and spleen, but not in brain. ESTs have been isolated from human normal blood, liver, placenta, and skin libraries, and human colon and lung cancer libraries. WebImmunohistochemistry analysis of OXER1 in paraffin-embedded human liver carcinoma tissue (cytoplasmic staining) and negative control (right, with PBS only). Samples were …
Oxer1
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WebOct 26, 2024 · OXER1 oxoeicosanoid receptor 1 [ (human)] Gene ID: 165140, updated on 26-Oct-2024. Summary. Enables G protein-coupled receptor activity and icosanoid binding … WebOXER1 is expressed in non-human primates, a wide range of other mammals, and various fish species and a model of allergic airways disease in cats, which express OXER1 and make 5-oxo-ETE, has recently been developed for such studies. In any event, cultured mouse MA-10 Leydig cells, while responding to
WebOXER1 ( 1 gene ) Coverage: 99% at 20x. Specimen Requirements: Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request) Test Limitations: All sequencing technologies have limitations. This analysis is performed by Next Generation Sequencing (NGS) and is designed to ... OXER1 is a G protein-coupled receptor (GPCR) that is structurally related to the hydroxy-carboxylic acid (HCA) family of G protein-coupled receptors whose three members are HCA1 , HCA2 (Niacin receptor 1), and HCA3 (Niacin receptor 2); OXER1 has 30.3%, 30.7%, and 30.7% amino acid sequence identity with … See more Oxoeicosanoid receptor 1 (OXER1) also known as G-protein coupled receptor 170 (GPR170) is a protein that in humans is encoded by the OXER1 gene located on human chromosome 2p21; it is the principal receptor … See more Orthologs of OXER1 are found in various mammalian species including opossums and several species of fish; however, mice and rats lack a clear ortholog of OXER1. This represents an … See more OXE-R couples to the G protein complex Gαi-Gβγ; when bound to a 5-oxo-ETE family member, OXE-R triggers this G protein complex to dissociate into its Gαi and Gβγ components. Gβγ appears to be the component most responsible for activating many of … See more • Bäck M, Powell WS, Dahlén SE, Drazen JM, Evans JF, Serhan CN, Shimizu T, Yokomizo T, Rovati GE (2014). "Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7". Br. J. Pharmacol. 171 (15): 3551–74. doi:10.1111/bph.12665 See more The OXER1 G protein-coupled receptor resembles the hydroxy carboxilic acid subfamily of G protein-coupled receptors, which besides … See more OXER1 is activated by 5-oxo-ETE, 5-HETE, and other members of the 5-Hydroxyicosatetraenoic acid family of arachidonic acid metabolites and thereby mediates this … See more • Eicosanoid receptor • 5-Hydroxyicosatetraenoic acid and 5-oxo-eicosatetraenoic acid • Niacin receptor 1 See more
WebJan 1, 2024 · OXER1 is a recently identified receptor, binding the arachidonic acid metabolic product 5-oxo-ETE, considered an inflammatory receptor, implicated in chemoattraction … WebDec 11, 2024 · High levels of OXER1 are observed in several BC cell lines and correlate with RACK1 expression and poor prognosis. Our data provide evidence on the role played by …
WebMar 13, 2024 · OXER1 is a GPCR receptor which is mainly expressed ininflammatory cells. OXER1 is highly selective for 5 oxo ETE, one of the most powerful chemo attractants and activators of eosinophils. Learn more. Recent News Mar 15, 2024 Liminal BioSciences Reports Fourth Quarter and Year Ended 2024 Financial Results Mar 13, 2024
WebOXER1 (oxoeicosanoid receptor 1) was deorphanized in 1993 and found to be the specific receptor for the arachidonic acid metabolite 5-oxo-ETE. roof tarisWebOct 28, 2024 · New Antagonists of the Membrane Androgen Receptor OXER1 from the ZINC Natural Product Database New Antagonists of the Membrane Androgen Receptor OXER1 … roof tar sprayWebOXER1 is a class A GPCR in the same classification branch as the leukotriene receptors.15It is particularly expressed in inflammatory cells (eosinophils, neutrophils, lymphocytes, and monocytes),... roof tarp hireWebReceptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5 (S)- hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic … roof tar spreaderWebOXER1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. roof tar sheetWebOXER1 Species Human Accession Number NM_148962.4 Alias Names 5-oxo-ETE G-protein coupled receptor; 5-oxo-ETE acid G-protein-coupled receptor 1; G-protein coupled receptor … roof tar shinglesWebFeb 1, 2024 · OXER1 Prostate cancer Breast cancer 1. Introduction During the last two decades, rapid androgen actions have been reported in different tissues/pathologies, mediated by specific receptors localized at the plasma membrane (mARs). Until recently, the identity of these mARs has not been elucidated. roof taping