Btg2 cancer
WebBTG2 can improve the radiosensitivity of breast cancer cells by affecting cell cycle distribution, enhancing radiation-induced apoptosis, and inhibiting DNA repair-related … WebBTG2 was highly expressed in HBE cells and was expressed at very low levels in lung cancer cell lines (A549, HCC827, NCI-H292, and 95-D). High miRNA-21 expression …
Btg2 cancer
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WebBTG2 expression was elevated upon IR exposure, in a dose-dependent but not a time-dependent manner. CCK-8 and EDU assays revealed that BTG2 overexpression … WebIn addition, the downregulation of BTG2 at the mRNA and protein level was also confirmed in luminal A breast tumor tissue, which was consistent with the results in vitro. These …
WebAug 9, 2016 · And overexpression of miR-27a-3p, but not miR-27a-5p, markedly promoted gastric cancer cell proliferation in vitro as well as tumor growth in vivo. Further experiments revealed that BTG2 was a direct and functional target of miR-27a-3p in gastric cancer and miR-27a-3p inhibition obviously up-regulated the expression of BTG2. WebBTG2 treatment exhibited inhibitory effect on PI3K/Akt pathway in MCF-7/ADR cells. Significance miR-27a-3p might be associated with resistance of breast cancer cells to adriamycin treatments, modulating cell proliferation and apoptosis by targeting BTG2 and promoting the PI3K/Akt pathway in breast cancer cells. miR-27a-3p/BTG2 axis might be …
WebOct 23, 2024 · In prostate cancer, BTG2 is a target of miR-32, miR-21, and its suppression results in disease initiation and progression, therapy resistance, and metastasis (Coppola et al., 2013; Jalava et al., 2012). These findings point to a predominantly tumor suppressive function for BTG2. WebTherefore, BTG2 is considered to be a novel tumor suppressor gene for many types of cancer, such as laryngeal cancer [10] gastric cancer [11], liver cancer and breast cancer [12].
WebBTG2. Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene ( B -cell t ranslocation g ene 2) [5] and in other mammals by the homologous Btg2 gene. [6] [7] This protein controls cell cycle progression and proneural ...
WebApr 8, 2024 · Circulating tumor cell. The CTC shedding process was studied in PDXs. E. Powell and colleagues developed paired triple-negative breast cancer (TNBC) PDX models with the only difference being p53 status. They reported that CTC shedding was found to be more related to total primary and metastatic tumor burden than p53 status [].Research on … coffee\\u0026covid.comWebApr 10, 2024 · Genetic classification helps to disclose molecular heterogeneity and therapeutic implications in diffuse large B-cell lymphoma (DLBCL). Using whole exome/genome sequencing, RNA-sequencing, and ... coffee\\u0026creamWebOct 1, 2024 · According to a research by Mourits et al., TLR10 does affect the induction of BCG-induced trained immunity in vitro. However, its role in vivo is still an open debate, as genetic variation in TLR10 gene does not affect the induction of trained immunity by BCG vaccination (Mourits et al. 2024 ). coffee \u0026 chocolate sayingsWebThe BTG2 expression is downregulated in many human cancers. It is an instantaneous early response gene and plays important roles in cell … coffee \u0026 cryptoWebPTEN activity inhibitor (VO-OHpic) treatment decreased BTG2 expression in RT-4 and PTEN-overexpressed T24 cells. Our results suggested that BTG2 functioned as a bladder cancer tumor suppressor gene, and was induced by p53 and PTEN. Modulation of BTG2 expression seems a promising way to treat human bladder cancer. coffee \u0026 conversation imagesWebAlthough widely deemed as a tumor suppressor gene, the role of B-cell translocation gene 2 (BTG2) in bladder cancer is still inconclusive. We investigated the role and regulatory … coffee\\u0026cream 歌詞WebBTG2. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. … coffee \u0026 crumb marion ohio